01 - Preheat air fryer to 400°F for 3-5 minutes.
02 - Whisk together eggs and milk in a shallow bowl until combined.
03 - Combine panko breadcrumbs, Parmesan, garlic powder, paprika, black pepper, and salt in a separate shallow bowl.
04 - Dip each tilapia fillet into egg mixture, allowing excess to drip off, then press firmly into breadcrumb mixture to coat evenly.
05 - Lightly spray air fryer basket with oil. Arrange breaded fillets in a single layer without overlapping.
06 - Cook for 10-12 minutes, flipping fillets halfway through, until golden brown and fish flakes easily with a fork.
07 - Transfer to plates and garnish with chopped parsley and lemon wedges.