01 - Preheat oven to 400°F and line a baking sheet with parchment paper or lightly grease it.
02 - Pat salmon fillets dry with paper towels and arrange on the baking sheet, skin-side down if applicable.
03 - In a small bowl, whisk olive oil, Cajun seasoning, smoked paprika, garlic powder, salt, black pepper, lime zest, and lime juice until well blended.
04 - Brush or spoon the spice mixture evenly over each salmon fillet.
05 - Top each fillet with a slice of lime to enhance flavor during baking.
06 - Bake for 12 to 15 minutes until salmon flakes easily with a fork and appears opaque in the center.
07 - Remove from oven, garnish with chopped cilantro or parsley if desired, and serve immediately.